Postdoctoral fellow in Breast cancer

Postdoctoral fellow in Breast cancer
Type of employment: Fixed-term employment, 2 years
Extent: 100 %
Location: Institute of Biomedicine, Göteborg
First day of employment: As agreed
Reference number: PER 2013/419
Sahlgrenska Cancer Center is a newly formed center within the University of Gothenburg with close proximity to Sahlgrenska University hospital in Sweden. The center is part of a strategic research focus on cancer within the Sahlgrenska Acadamy and consists of an exciting mix of basic and clinical researchers dedicated to multidisciplinary studies of cancer with highly set translational ambitions.
One postdoctoral research position is now available in Professor Göran Landberg´s research group at the Sahlgrenska Cancer Center.
Subject area
Breast cancer
Specific subject description
Breast cancer represents many different diseases with partly contrasting clinical behaviours and underlying genetic alterations. In order to define novel and more efficient treatment schedules for breast cancer as well as define the subgroup of patients that will benefit from a particular treatment we need to know more about the basic defects occurring in cancer. It is also clear that the microenvironment influences the tumour cells and behaviours and hypoxia influences both the primary tumour site as well as potential metastatic niches. Within the project you will use a combination of experimental models and studies of clinical samples and specifically investigate how hypoxia will influence breast cancer initiating cells. Novel targets for therapy will further be developed using data from various high through-put screening methods. Within the project there will be a focus on breast cancer but other tumour types might be used to gain additional insights in the interplay between the microenvironment and key tumour properties.
Job assignments
The projects will focus on breast cancer and the interplay between microenvironment and key tumour properties. Within the project you will use a combination of experimental models and studies of clinical samples and specifically investigate how hypoxia will influence breast cancer stem cells. Novel targets for therapy will further be developed using various high through-put screening methods.
Main duties and responsibilities under the supervision of Professor Landberg:
- To undertake research activities in connection with the project outlined
- To maintain records of research performed
- To undertake draft report writing as requested
- To prepare material for publication
- To present material at research and professional conferences
Eligibility
Essential
- PhD Qualification
- Publication record in peer reviewed journals
- A background in cell biology
- Experience in the in vitro propagation of primary cells and cell lines
- Ability to work independently within an agreed framework
- Willingness to learn new experimental techniques
- Excellent communication skills on paper and verbally
- Good organisational skills
- Ability to work as part of a team
Desirable
- Experience in tumour biology
- Experience of work within the biomedical industry
- Experience in cell line model systems
- Experience in cell line model systems
- Experience in immunohistochemical studies of tumour cells
- Experience of supervising technical staff and student projects
Assessment
An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here.