Postdoctoral fellow

We are currently recruiting a postdoctoral fellow for a fulltime position for two years.The position is within Department of Psychiatry and Neurochemistry at the Institute for Neuroscience and Physiology at the Sahlgrenska Academy at the University of Gothenburg.

Project: Biological activity of amyloid-related proteins in Alzheimer's disease

Alzheimer s disease (AD) is characterised by deposits of amyloid B (AB) in senile plaques in the cerebral cortex.A wealth of studies suggest that AB is neurotoxic and that its earliest AD-promoting effect is related to inhibition of hippocampal long-term potentiation, which is the electrophysiological correlate to memory consolidation.The general aim of the project is to test the hypothesis that a dysbalance in the production and/or clearance of AB is a specific feature of AD.Using cell, tissue and zebrafish models, we will address: (i) how the different AB isoforms are produced, (ii) if certain AB isoforms are more synaptotoxic than others, and (iii) if APP- and AB-processing changes in response to synaptic activity.

Requirements: PhD in any field relevant to the projects listed above obtained within 3 years from last application date.A proven track record is required with publications in peer reviewed international journals and very good analytical skills.

Application: The application shall be written in English and include CV, a conclusive cover letter and a list over publications.

Send your signed application together with examination certificates to: Registrar, Sahlgrenska Academy at University of Gothenburg, Box 400, SE-405 30 Gothenburg, Sweden.The final date to reach the Registrar is May 12th 2010.