Senior Scientist - In vitro

Are you an experienced cell biologist with a solid experience of stem- and primary cell culture and methodologies for cell characterization? Are you passionate about doing hands-on high-quality lab-work for the development of novel cell-based therapies? Join us and be a key player in the build of our Biopharmaceuticals R&D Cell Therapy department. Together we will push the boundaries of Science!

At AstraZeneca, you will be empowered to be innovative and creative where difference is valued. We thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. The role is placed at AstraZeneca's dynamic R&D site in Gothenburg, Sweden, where you will work in an international setting at the fore front of Cell Therapy science.

Biopharmaceuticals R&D is committed to the development of next generation innovative medicines and we are building a Cell Therapy department with the goal to establish AstraZeneca as a world-leader in Cell Therapy across disease areas within Cardiovascular, Renal and Metabolism (CVRM) and Respiratory and Inflammation (R&I). The department will bring together >50 specialists to support the organization with cell therapy expertise and capabilities, and we are working in close collaboration with experts across AstraZeneca globally to leverage the existing and emerging platforms in cell technologies, new modalities, universal cell lines and CRISPR-mediated genome editing.

What you'll do

This role provides an opportunity to work in an international, highly cross disciplinary environment with ground-breaking techniques and technologies within areas such as stem cell biology and precise genome editing. You will work together with other vitro scientists and collaborate with disease area specialists and in vivo scientists to develop our scientific capabilities and ensure efficient progress of Cell Therapy projects.

The role is focused on laboratory-based activities and you will use your scientific expertise to design and execute experiments and to deliver high quality data. Your biggest impact will be through practical and scientific contributions to support projects in compliance with AstraZeneca corporate responsibility, policies and relevant safety standards. You will be working in a flexible project-driven organization with several ongoing projects in parallel.

In this role it is essential to have good social and communication skills, be collaborative and a strong team player. You should enjoy and feel challenged by working in a multitasking lab environment and be able to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude. Good organizational, data management and documentation skills are required, and you should be comfortable in presenting your results internally as well as at external meetings.

Accountability includes:

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Design and perform experiments in vitro to generate cell populations of therapeutic relevance.
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Characterize and quantify cell phenotype/identity using readouts like qPCR, flow cytometry and imaging-based readouts.
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Develop and troubleshoot protocol for in vitro culture and differentiation of various cell types including primary cells and pluripotent stem cells as needed.
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Independently analyse and report data to support project decisions and communicate relevant information between distinct projects within the bioscience department as well as across other functions.

Essential for the role

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Ph.D. in Cell Biology or a related field with relevant academic or industrial experience.
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Minimum 5+ years' hands-on experience of in vitro cell culture (primary and/or pluripotent stem cells).
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Extensive hands-on experience of several standard analysis techniques like qPCR, flow cytometry, imaging analysis or confocal imaging.
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Excellent experimental standards, scientific drive and experience of independent lab work.

Desirable for the role

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Experience of hESC or hiPSC culture and differentiation protocol development, e.g. intermediate mesoderm, endoderm and hematopoietic (incl. Monocytes/macrophages) lineages are highly valued.
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Experience of primary or stem cell culture in 3D systems.
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Experience of bioreactor-based cell culture or stem or primary cells.

So, what's next?

Can you already see yourself in this role? Good, because we can't wait to hear from you!

Welcome with your application no later than October 2nd 2022. We will review the applications continuously so please apply at your earliest convenience.

Where can I find out more?

Cell Therapy Biopharmaceuticals R&D: Link

Global Gothenburg: Link

Our Gothenburg site: Link

Life in Gothenburg: Link

Why AstraZeneca?

Our Gothenburg site is one of AstraZeneca's three strategic R&D centers. With more than 2,400 employees from over than 50 countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.