Solid State Analytical Chemist to AstraZeneca in Gothenburg

Solid State Analytical Chemist
Solid State Analytical Chemist to Pharmaceutical Sciences

This is a unique opportunity for an enthusiastic, innovative and motivated scientist to join the Pharmaceutical Science teams at our site at AstraZeneca, Gothenburg. Join us and be an active member of a multi skilled group, working closely together with analysts, formulators, chemists and biologists in our common effort to drive the projects forward. The one-year assignment starts February 1st.



Business: Dfind Science & Engineering

City: Gothenburg

The Arena

AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, meaningful medicines and healthcare solutions that enrich the lives of patients. Pharmaceutical Sciences is a newly created department within our Innovative Medicines and Early Development (IMED) Biotech unit. The vision for Pharmaceutical Sciences is to deliver the therapies of the future through scientific leadership in drug delivery, design of synthetic routes and manufacturing of Active Pharmaceutical Ingredients (API). Our portfolio of projects span traditional small molecules to RNA based therapies across AstraZeneca’s therapy areas.

We now have an open temporary position and are looking for a skilled experimentalist who enjoys being in the lab and working in a multi skilled team, collaborating closely with analysts, formulators and chemists. As a Solid State Analytical Chemist you will influence the solid state properties of new drug substances, you will plan and perform experiments to crystallise and characterise salts and polymorphs and assess the solid state properties by using a wide range of different techniques.



The Role

• Performing solid state analyses (XRPD, DSC, TGA and more) on substances and formulations.
• Performing experimental and theoretical risk assessments of solid forms.
• Leading investigations and trouble-shooting related to solid form in multiple projects and with short timelines.
• Acting as solid state expert in Pharmaceutical Sciences project teams.
• Accountability for maintenance, calibration and training on solid state analytical instruments.
• Apply technical knowledge to the evaluation of new technology/processes. Present own work and collaborate with specialist scientific and/or technology networks..


Examples of skills of importance for the role are the following:

• A good understanding of solid state properties, choice of solid state form and associated phase transitions of drug substance, and how these link to formulation stability and processability. A good knowledge of techniques to characterize this e.g.XRPD, DSC, GVS, TGA and vibrational spectroscopy.
• A knowledge of salt- and polymorph screening and crystallization process development
• A knowledge of excipients and the solid state of excipients used for pharmaceuticals.
• Knowledge of imaging techniques, eg SEM and optical microscopy.
• An understanding of powders, including analysis techniques for determining physical properties, eg particle size and particle size distribution, shape, density and powder rheology.


The successful applicant will be given the opportunity to contribute to the development of the scientific area via material science/solid state networks.



This is a unique opportunity for an innovative and motivated Material Science/Solid state expert to join the Product Development team, at our site in Mölndal.



Requirements

PhD or BSC/MSc in a relevant subject with some years of work experience.

Experience of individual and non-supervised laboratory work

Experience of relevant analytical techniques

GMP awareness/experience.

Good communication skills coupled with the ability to work to tight timelines.



Skills and capabilities

• Ability to work flexibly and adapt to changing priorities.
• Ability to utilize scientific and innovative thinking.
• Ability to work both in a team and independently, using your own initiative.
• Ability to attend to details and at the same time understand their connection and impact on the bigger picture.
• Enthusiasm for laboratory based work.
• Demonstrate high degree of personal credibility.
• Deliver well documented data of right quality in a timely manner.
• Good verbal and written communication skills.


Deadline for applications: 2016-12-20.



More information: Stefan Bäckström, stefan.backstrom@dfind.se



Organization/Business description:
Dfind Science & Engineering är ett konsult- och rekryteringsföretag som erbjuder en omväxlande karriär som konsult inom teknik och naturvetenskap.

Hos oss har du möjlighet att utveckla dina kunskaper och bygga CV genom olika uppdrag hos våra utvecklings-, forsknings- och produktionsintensiva kunder samtidigt som du får stöd och vägledning från din konsultchef.

Vi är auktoriserade via Almega och följer deras kollektivavtal. Vi har dessutom förmåner som friskvårdsbidrag, företagshälsovård, försäkringar och rabatt på träningskort.

Välkommen till oss för en omväxlande och trygg karriär som konsult.